Cargando…
RAB43 facilitates cross-presentation of cell-associated antigens by CD8α(+) dendritic cells
In this study, to examine cross-presentation by classical dendritic cells (DCs; cDCs), we evaluated the role of RAB43, a protein found to be selectively expressed by Batf3-dependent CD8α(+) and CD103(+) compared with other DC subsets and immune lineages. Using a specific monoclonal antibody, we loca...
Autores principales: | Kretzer, Nicole M., Theisen, Derek J., Tussiwand, Roxane, Briseño, Carlos G., Grajales-Reyes, Gary E., Wu, Xiaodi, Durai, Vivek, Albring, Jörn, Bagadia, Prachi, Murphy, Theresa L., Murphy, Kenneth M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154939/ https://www.ncbi.nlm.nih.gov/pubmed/27899443 http://dx.doi.org/10.1084/jem.20160597 |
Ejemplares similares
-
Batf3 maintains Irf8 autoactivation for commitment of a CD8α(+) cDC clonogenic progenitor
por: Grajales-Reyes, Gary E., et al.
Publicado: (2015) -
Mafb lineage tracing to distinguish macrophages from other immune lineages reveals dual identity of Langerhans cells
por: Wu, Xiaodi, et al.
Publicado: (2016) -
Quality of TCR signaling encoded by differential enhancer affinities for the composite BATF-IRF4 transcription factor complex
por: Iwata, Arifumi, et al.
Publicado: (2017) -
L-Myc expression by dendritic cells is required for optimal T-cell priming
por: Wumesh, KC, et al.
Publicado: (2014) -
Altered compensatory cytokine signaling underlies the discrepancy between Flt3(–/–) and Flt3l(–/–) mice
por: Durai, Vivek, et al.
Publicado: (2018)