Dampened antiviral immunity to intravaginal exposure to RNA viral pathogens allows enhanced viral replication

Understanding the host immune response to vaginal exposure to RNA viruses is required to combat sexual transmission of this class of pathogens. In this study, using lymphocytic choriomeningitis virus (LCMV) and Zika virus (ZIKV) in wild-type mice, we show that these viruses replicate in the vaginal...

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Detalles Bibliográficos
Autores principales: Khan, Shahzada, Woodruff, Erik M., Trapecar, Martin, Fontaine, Krystal A., Ezaki, Ashley, Borbet, Timothy C., Ott, Melanie, Sanjabi, Shomyseh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154948/
https://www.ncbi.nlm.nih.gov/pubmed/27852793
http://dx.doi.org/10.1084/jem.20161289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154948/
https://www.ncbi.nlm.nih.gov/pubmed/27852793
http://dx.doi.org/10.1084/jem.20161289

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