Plasmacytoid Dendritic Cells Respond Directly to Apoptotic Cells by Secreting Immune Regulatory IL-10 or IFN-α

Plasmacytoid dendritic cells (pDCs) play a pivotal role in driving the autoimmune disease systemic lupus erythematosus, via the secretion of IFN-α in response to nuclear self-antigens complexed with autoantibodies. Apoptotic cells, generated at sites of inflammation or secondary lymphoid organs, are...

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Detalles Bibliográficos
Autores principales: Simpson, Joanne, Miles, Katherine, Trüb, Marta, MacMahon, Roisin, Gray, Mohini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155015/
https://www.ncbi.nlm.nih.gov/pubmed/28018356
http://dx.doi.org/10.3389/fimmu.2016.00590

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155015/
https://www.ncbi.nlm.nih.gov/pubmed/28018356
http://dx.doi.org/10.3389/fimmu.2016.00590

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