Cargando…

Comparing expression and activity of PCSK9 in SPRET/EiJ and C57BL/6J mouse strains shows lack of correlation with plasma cholesterol()

OBJECTIVE: Low-density lipoprotein receptor (LDLR) and proprotein convertase subtilisin/kexin type 9 (PCSK9) are opposing regulators of plasma LDL-cholesterol levels. The PCSK9 gene exhibits many single or compound polymorphisms within or among mammalian species. This is case between the SPRET/EiJ (...

Descripción completa

Detalles Bibliográficos
Autores principales: Sirois, Francine, Chrétien, Michel, Mbikay, Majambu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155046/
https://www.ncbi.nlm.nih.gov/pubmed/27995077
http://dx.doi.org/10.1016/j.ymgmr.2016.11.006