Freeze Dried Quetiapine-Nicotinamide Binary Solid Dispersions: A New Strategy for Improving Physicochemical Properties and Ex Vivo Diffusion

Improving the physicochemical properties and oral bioavailability of quetiapine fumarate (QF) enabling enhanced antipsychotic attributes are the main aims of this research. The freeze dried solid dispersion strategy was adopted using nicotinamide (NIC) as highly soluble coformer. The prepared disper...

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Detalles Bibliográficos
Autores principales: Ali, Ahmed Mahmoud Abdelhaleem, Al-Remawi, Mayyas Mohammad Ahmad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155126/
https://www.ncbi.nlm.nih.gov/pubmed/28042494
http://dx.doi.org/10.1155/2016/2126056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155126/
https://www.ncbi.nlm.nih.gov/pubmed/28042494
http://dx.doi.org/10.1155/2016/2126056

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