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Slit-Robo GTPase-Activating Protein 2 as a metastasis suppressor in osteosarcoma

Osteosarcoma is the most common primary bone tumor, with metastatic disease responsible for most treatment failure and patient death. A forward genetic screen utilizing Sleeping Beauty mutagenesis in mice previously identified potential genetic drivers of osteosarcoma metastasis, including Slit-Robo...

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Detalles Bibliográficos
Autores principales: Marko, Tracy A., Shamsan, Ghaidan A., Edwards, Elizabeth N., Hazelton, Paige E., Rathe, Susan K., Cornax, Ingrid, Overn, Paula R., Varshney, Jyotika, Diessner, Brandon J., Moriarity, Branden S., O’Sullivan, M. Gerard, Odde, David J., Largaespada, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155223/
https://www.ncbi.nlm.nih.gov/pubmed/27966608
http://dx.doi.org/10.1038/srep39059