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Slit-Robo GTPase-Activating Protein 2 as a metastasis suppressor in osteosarcoma
Osteosarcoma is the most common primary bone tumor, with metastatic disease responsible for most treatment failure and patient death. A forward genetic screen utilizing Sleeping Beauty mutagenesis in mice previously identified potential genetic drivers of osteosarcoma metastasis, including Slit-Robo...
Autores principales: | Marko, Tracy A., Shamsan, Ghaidan A., Edwards, Elizabeth N., Hazelton, Paige E., Rathe, Susan K., Cornax, Ingrid, Overn, Paula R., Varshney, Jyotika, Diessner, Brandon J., Moriarity, Branden S., O’Sullivan, M. Gerard, Odde, David J., Largaespada, David A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155223/ https://www.ncbi.nlm.nih.gov/pubmed/27966608 http://dx.doi.org/10.1038/srep39059 |
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