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Surfactin inducing mitochondria-dependent ROS to activate MAPKs, NF-κB and inflammasomes in macrophages for adjuvant activity

Surfactin, a natural lipopeptide, can be used both as parenteral and non-parenteral adjuvant for eliciting immune response. However, the mechanisms that confer its adjuvant properties have not been fully explored. By staining with NHS-Rhodamine B labeled surfactin and Mito-Tracker Green, we found su...

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Detalles Bibliográficos
Autores principales: Gan, Ping, Gao, Zhenqiu, Zhao, Xiuyun, Qi, Gaofu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155226/
https://www.ncbi.nlm.nih.gov/pubmed/27966632
http://dx.doi.org/10.1038/srep39303