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Surfactin inducing mitochondria-dependent ROS to activate MAPKs, NF-κB and inflammasomes in macrophages for adjuvant activity

Surfactin, a natural lipopeptide, can be used both as parenteral and non-parenteral adjuvant for eliciting immune response. However, the mechanisms that confer its adjuvant properties have not been fully explored. By staining with NHS-Rhodamine B labeled surfactin and Mito-Tracker Green, we found su...

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Detalles Bibliográficos
Autores principales:	Gan, Ping, Gao, Zhenqiu, Zhao, Xiuyun, Qi, Gaofu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155226/ https://www.ncbi.nlm.nih.gov/pubmed/27966632 http://dx.doi.org/10.1038/srep39303

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