Multivalent pIX phage display selects for distinct and improved antibody properties

Phage display screening readily allows for the identification of a multitude of antibody specificities, but to identify optimal lead candidates remains a challenge. Here, we direct the antibody-capsid fusion away from the signal sequence-dependent secretory SEC pathway in E. coli by utilizing the in...

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Detalles Bibliográficos
Autores principales: Høydahl, Lene S., Nilssen, Nicolay R., Gunnarsen, Kristin S., Pré, M. Fleur du, Iversen, Rasmus, Roos, Norbert, Chen, Xi, Michaelsen, Terje E., Sollid, Ludvig M., Sandlie, Inger, Løset, Geir Å.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155289/
https://www.ncbi.nlm.nih.gov/pubmed/27966617
http://dx.doi.org/10.1038/srep39066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155289/
https://www.ncbi.nlm.nih.gov/pubmed/27966617
http://dx.doi.org/10.1038/srep39066

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