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Enhanced Human-Induced Pluripotent Stem Cell Derived Cardiomyocyte Maturation Using a Dual Microgradient Substrate

[Image: see text] Human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) raise many possibilities for cardiac research but they exhibit an immature phenotype, which influences experimental outcomes. The aim of our research is to investigate the effects of a topographical gradient subs...

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Detalles Bibliográficos
Autores principales: Huethorst, E., Hortigon, M., Zamora-Rodriguez, V., Reynolds, P. M., Burton, F., Smith, G., Gadegaard, N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155309/
https://www.ncbi.nlm.nih.gov/pubmed/27990488
http://dx.doi.org/10.1021/acsbiomaterials.6b00426