The cell-autonomous mechanisms underlying the activity of metformin as an anticancer drug

The biguanide drug metformin profoundly affects cell metabolism, causing an impairment of the cell energy balance and triggering a plethora of pleiotropic effects that vary depending on the cellular or environmental context. Interestingly, a decade ago, it was observed that metformin-treated diabeti...

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Detalles Bibliográficos
Autores principales: Sacco, Francesca, Calderone, Alberto, Castagnoli, Luisa, Cesareni, Gianni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155371/
https://www.ncbi.nlm.nih.gov/pubmed/27875520
http://dx.doi.org/10.1038/bjc.2016.385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155371/
https://www.ncbi.nlm.nih.gov/pubmed/27875520
http://dx.doi.org/10.1038/bjc.2016.385

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