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Endogenous programmed death ligand-1 restrains the development and onset of Sjӧgren’s syndrome in non-obese diabetic mice

Programmed death-ligand 1 (PD-L1) down-modulates various immune responses by engaging the co-inhibitory receptor programmed death-1. Expression of PD-L1 and programmed death-1 is elevated in the salivary glands of patients with Sjögren’s syndrome (SS). The objective of this study is to define the ro...

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Detalles Bibliográficos
Autores principales: Zhou, Jing, Jin, Jun-O., Kawai, Toshihisa, Yu, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155421/
https://www.ncbi.nlm.nih.gov/pubmed/27966604
http://dx.doi.org/10.1038/srep39105