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Boosting Adaptive Immunity: A New Role for PAFR Antagonists

We have previously shown that the Platelet-Activating Factor Receptor (PAFR) engagement in murine macrophages and dendritic cells (DCs) promotes a tolerogenic phenotype reversed by PAFR-antagonists treatment in vitro. Here, we investigated whether a PAFR antagonist would modulate the immune response...

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Detalles Bibliográficos
Autores principales: Koga, Marianna M., Bizzarro, Bruna, Sá-Nunes, Anderson, Rios, Francisco J., Jancar, Sonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155422/
https://www.ncbi.nlm.nih.gov/pubmed/27966635
http://dx.doi.org/10.1038/srep39146