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Alternative exon usage creates novel transcript variants of tumor suppressor SHREW-1 gene with differential tissue expression profile

Shrew-1, also called AJAP1, is a transmembrane protein associated with E-cadherin-mediated adherence junctions and a putative tumor suppressor. Apart from its interaction with β-catenin and involvement in E-cadherin internalization, little structure or function information exists. Here we explored s...

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Detalles Bibliográficos
Autores principales: Klemmt, Petra A. B., Resch, Eduard, Smyrek, Isabell, Engels, Knut, Stelzer, Ernst H. K., Starzinski-Powitz, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155531/
https://www.ncbi.nlm.nih.gov/pubmed/27870635
http://dx.doi.org/10.1242/bio.019463