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Eyes shut homolog is required for maintaining the ciliary pocket and survival of photoreceptors in zebrafish

Mutations in the extracellular matrix protein eyes shut homolog (EYS) cause photoreceptor degeneration in patients with retinitis pigmentosa 25 (RP25). Functions of EYS remain poorly understood, due in part to the lack of an EYS gene in mouse. We investigated the localization of vertebrate EYS prote...

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Detalles Bibliográficos
Autores principales: Yu, Miao, Liu, Yu, Li, Jing, Natale, Brianna N., Cao, Shuqin, Wang, Dongliang, Amack, Jeffrey D., Hu, Huaiyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155541/
https://www.ncbi.nlm.nih.gov/pubmed/27737822
http://dx.doi.org/10.1242/bio.021584