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Preclinical optimization of a broad-spectrum anti-bladder cancer tri-drug regimen via the Feedback System Control (FSC) platform

Therapeutic outcomes of combination chemotherapy have not significantly advanced during the past decades. This has been attributed to the formidable challenges of optimizing drug combinations. Testing a matrix of all possible combinations of doses and agents in a single cell line is unfeasible due t...

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Detalles Bibliográficos
Autores principales: Liu, Qi, Zhang, Cheng, Ding, Xianting, Deng, Hui, Zhang, Daming, Cui, Wei, Xu, Hongwei, Wang, Yingwei, Xu, Wanhai, Lv, Lei, Zhang, Hongyu, He, Yinghua, Wu, Qiong, Szyf, Moshe, Ho, Chih-Ming, Zhu, Jingde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155572/
https://www.ncbi.nlm.nih.gov/pubmed/26088171
http://dx.doi.org/10.1038/srep11464