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INC280, an orally available small molecule inhibitor of c-MET, reduces migration and adhesion in ovarian cancer cell models

5-year survival rates for ovarian cancer are approximately 40%, and for women diagnosed at late stage (the majority), just 27%. This indicates a dire need for new treatments to improve survival rates. Recent molecular characterization has greatly improved our understanding of the disease and allowed...

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Detalles Bibliográficos
Autores principales: Moran-Jones, Kim, Brown, Laura M., Samimi, Goli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155610/
https://www.ncbi.nlm.nih.gov/pubmed/26138303
http://dx.doi.org/10.1038/srep11749