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DNA methylation as a potential diagnosis indicator for rapid discrimination of rare cancer cells and normal cells

The global DNA methylation degree may be a ubiquitous and early biomarker to distinguish cancer cells from benign cells. However, its usefulness in clinical diagnosis was scarcely demonstrated, because the cancer cells isolated from patients were usually very rare. Even if 10 mL of peripheral blood...

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Detalles Bibliográficos
Autores principales: Si, Xingyu, Zhao, Yaoyao, Yang, Chengdui, Zhang, Sichun, Zhang, Xinrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155617/
https://www.ncbi.nlm.nih.gov/pubmed/26139010
http://dx.doi.org/10.1038/srep11882