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Divergent Synthesis of Chondroitin Sulfate Disaccharides and Identification of Sulfate Motifs that Inhibit Triple Negative Breast Cancer

Glycosaminoglycans (GAGs) regulate many important physiological processes. A pertinent issue to address is whether GAGs encode important functional information via introduction of position specific sulfate groups in the GAG structure. However, procurement of pure, homogenous GAG motifs to probe the...

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Detalles Bibliográficos
Autores principales: Wei Poh, Zhong, Heng Gan, Chin, Lee, Eric J., Guo, Suxian, Yip, George W., Lam, Yulin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155627/
https://www.ncbi.nlm.nih.gov/pubmed/26400608
http://dx.doi.org/10.1038/srep14355