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Reprogramming antitumor immunity against chemoresistant ovarian cancer by a CXCR4 antagonist-armed viral oncotherapy

Ovarian cancer remains the most lethal gynecologic malignancy owing to late detection, intrinsic and acquired chemoresistance, and remarkable heterogeneity. Here, we explored approaches to inhibit metastatic growth of murine and human ovarian tumor variants resistant to paclitaxel and carboplatin by...

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Detalles Bibliográficos
Autores principales: Komorowski, Marcin P, McGray, AJ Robert, Kolakowska, Agnieszka, Eng, Kevin, Gil, Margaret, Opyrchal, Mateusz, Litwinska, Bogumila, Nemeth, Michael J, Odunsi, Kunle O, Kozbor, Danuta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155641/
https://www.ncbi.nlm.nih.gov/pubmed/28035333
http://dx.doi.org/10.1038/mto.2016.34