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Src kinase as a mediator of convergent molecular abnormalities leading to NMDAR hypoactivity in schizophrenia
Numerous investigations support decreased glutamatergic signaling as a pathogenic mechanism of schizophrenia: yet molecular underpinnings for such dysregulation are largely unknown. In the postmortem dorsolateral prefrontal cortex, we found striking decreases in tyrosine phosphorylation of N-methyl-...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156326/ https://www.ncbi.nlm.nih.gov/pubmed/25330739 http://dx.doi.org/10.1038/mp.2014.115 |