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Effect of Regulatory Element DNA Methylation on Tissue-Type Plasminogen Activator Gene Expression
Expression of the tissue-type plasminogen activator gene (t-PA; gene name PLAT) is regulated, in part, by epigenetic mechanisms. We investigated the relationship between PLAT methylation and PLAT expression in five primary human cell types and six transformed cell lines. CpG methylation was analyzed...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156355/ https://www.ncbi.nlm.nih.gov/pubmed/27973546 http://dx.doi.org/10.1371/journal.pone.0167588 |