Vaccinia Virus Immunomodulator A46: A Lipid and Protein-Binding Scaffold for Sequestering Host TIR-Domain Proteins

Vaccinia virus interferes with early events of the activation pathway of the transcriptional factor NF-kB by binding to numerous host TIR-domain containing adaptor proteins. We have previously determined the X-ray structure of the A46 C-terminal domain; however, the structure and function of the A46...

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Detalles Bibliográficos
Autores principales: Fedosyuk, Sofiya, Bezerra, Gustavo Arruda, Radakovics, Katharina, Smith, Terry K., Sammito, Massimo, Bobik, Nina, Round, Adam, Ten Eyck, Lynn F., Djinović-Carugo, Kristina, Usón, Isabel, Skern, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156371/
https://www.ncbi.nlm.nih.gov/pubmed/27973613
http://dx.doi.org/10.1371/journal.ppat.1006079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156371/
https://www.ncbi.nlm.nih.gov/pubmed/27973613
http://dx.doi.org/10.1371/journal.ppat.1006079

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