Long-Lasting WNT-TCF Response Blocking and Epigenetic Modifying Activities of Withanolide F in Human Cancer Cells

The WNT-TCF signaling pathway participates in adult tissue homeostasis and repair, and is hyperactive in a number of human diseases including cancers of the colon. Whereas to date there are no antagonists approved for patient use, a potential problem for their sustained use is the blockade of WNT si...

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Detalles Bibliográficos
Autores principales: Seth, Chandan, Mas, Christophe, Conod, Arwen, Mueller, Jens, Siems, Karsten, Kuciak, Monika, Borges, Isabel, Ruiz i Altaba, Ariel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156407/
https://www.ncbi.nlm.nih.gov/pubmed/27973612
http://dx.doi.org/10.1371/journal.pone.0168170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156407/
https://www.ncbi.nlm.nih.gov/pubmed/27973612
http://dx.doi.org/10.1371/journal.pone.0168170

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