Ginkgolide B Exerts Cardioprotective Properties against Doxorubicin-Induced Cardiotoxicity by Regulating Reactive Oxygen Species, Akt and Calcium Signaling Pathways In Vitro and In Vivo

The aim of this study was to evaluate the effect of Ginkgolide B (GB) on doxorubicin (DOX) induced cardiotoxicity in vitro and in vivo. Rat cardiomyocyte cell line H9c2 was pretreated with GB and subsequently subjected to doxorubicin treatment. Cell viability and cell apoptosis were assessed by MTT...

Descripción completa

Detalles Bibliográficos
Autores principales: Gao, Junqing, Chen, Tao, Zhao, Deqiang, Zheng, Jianpu, Liu, Zongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156426/
https://www.ncbi.nlm.nih.gov/pubmed/27973574
http://dx.doi.org/10.1371/journal.pone.0168219

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156426/
https://www.ncbi.nlm.nih.gov/pubmed/27973574
http://dx.doi.org/10.1371/journal.pone.0168219

Ejemplares similares