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A Period of Controlled Elevation of IOP (CEI) Produces the Specific Gene Expression Responses and Focal Injury Pattern of Experimental Rat Glaucoma

PURPOSE: We determine if several hours of controlled elevation of IOP (CEI) will produce the optic nerve head (ONH) gene expression changes and optic nerve (ON) damage pattern associated with early experimental glaucoma in rats. METHODS: The anterior chambers of anesthetized rats were cannulated and...

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Detalles Bibliográficos
Autores principales: Morrison, John C., Cepurna, William O., Tehrani, Shandiz, Choe, Tiffany E., Jayaram, Hari, Lozano, Diana C., Fortune, Brad, Johnson, Elaine C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156512/
https://www.ncbi.nlm.nih.gov/pubmed/27942722
http://dx.doi.org/10.1167/iovs.16-20573