The role of gigaxonin in the degradation of the glial-specific intermediate filament protein GFAP

Alexander disease (AxD) is a primary genetic disorder of astrocytes caused by dominant mutations in the gene encoding the intermediate filament (IF) protein GFAP. This disease is characterized by excessive accumulation of GFAP, known as Rosenthal fibers, within astrocytes. Abnormal GFAP aggregation...

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Detalles Bibliográficos
Autores principales: Lin, Ni-Hsuan, Huang, Yu-Shan, Opal, Puneet, Goldman, Robert D., Messing, Albee, Perng, Ming-Der
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156539/
https://www.ncbi.nlm.nih.gov/pubmed/27798231
http://dx.doi.org/10.1091/mbc.E16-06-0362

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156539/
https://www.ncbi.nlm.nih.gov/pubmed/27798231
http://dx.doi.org/10.1091/mbc.E16-06-0362

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