Motor Dysfunctions and Neuropathology in Mouse Models of Spinocerebellar Ataxia Type 2: A Comprehensive Review

Spinocerebellar ataxia type 2 (SCA2) is an autosomal dominant ataxia caused by an expansion of CAG repeats in the exon 1 of the gene ATXN2, conferring a gain of toxic function that triggers the appearance of the disease phenotype. SCA2 is characterized by several symptoms including progressive gait...

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Detalles Bibliográficos
Autores principales: Alves-Cruzeiro, João M. Da Conceição, Mendonça, Liliana, Pereira de Almeida, Luís, Nóbrega, Clévio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156697/
https://www.ncbi.nlm.nih.gov/pubmed/28018166
http://dx.doi.org/10.3389/fnins.2016.00572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156697/
https://www.ncbi.nlm.nih.gov/pubmed/28018166
http://dx.doi.org/10.3389/fnins.2016.00572

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