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Modulation of Muscle Fiber Compositions in Response to Hypoxia via Pyruvate Dehydrogenase Kinase-1

Muscle fiber-type changes in hypoxic conditions in accordance with pyruvate dehydrogenase kinase (Pdk)-1 and hypoxia inducible factor (Hif)-1α were investigated in rats. Hif-1α and its down-stream molecule Pdk-1 are well known for readily response to hypoxia. We questioned their roles in relation to...

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Detalles Bibliográficos
Autores principales: Nguyen, Daniel D., Kim, Gyuyoup, Pae, Eung-Kwon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156708/
https://www.ncbi.nlm.nih.gov/pubmed/28018235
http://dx.doi.org/10.3389/fphys.2016.00604