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High-Fat Diet Augments VPAC1 Receptor-Mediated PACAP Action on the Liver, Inducing LAR Expression and Insulin Resistance

Pituitary adenylate cyclase-activating polypeptide (PACAP) acts on multiple processes of glucose and energy metabolism. PACAP potentiates insulin action in adipocytes and insulin release from pancreatic β-cells, thereby enhancing glucose tolerance. Contrary to these effects at organ levels, PACAP nu...

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Detalles Bibliográficos
Autores principales: Nakata, Masanori, Zhang, Boyang, Yang, Yifei, Okada, Takashi, Shintani, Norihito, Hashimoto, Hitoshi, Yada, Toshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156820/
https://www.ncbi.nlm.nih.gov/pubmed/28044141
http://dx.doi.org/10.1155/2016/9321395