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High-Fat Diet Augments VPAC1 Receptor-Mediated PACAP Action on the Liver, Inducing LAR Expression and Insulin Resistance
Pituitary adenylate cyclase-activating polypeptide (PACAP) acts on multiple processes of glucose and energy metabolism. PACAP potentiates insulin action in adipocytes and insulin release from pancreatic β-cells, thereby enhancing glucose tolerance. Contrary to these effects at organ levels, PACAP nu...
Autores principales: | Nakata, Masanori, Zhang, Boyang, Yang, Yifei, Okada, Takashi, Shintani, Norihito, Hashimoto, Hitoshi, Yada, Toshihiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156820/ https://www.ncbi.nlm.nih.gov/pubmed/28044141 http://dx.doi.org/10.1155/2016/9321395 |
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