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Metabolomic Study on Idiosyncratic Liver Injury Induced by Different Extracts of Polygonum multiflorum in Rats Integrated with Pattern Recognition and Enriched Pathways Analysis

Currently, numerous liver injury cases related to a famous Chinese herb- Polygonum Multiflorum (Heshouwu in Chinese) have attracted great attention in many countries. Our previous work showed that Heshouwu-induced hepatotoxicity belonged to idiosyncratic drug-induced liver injury (IDILI). Unfortunat...

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Detalles Bibliográficos
Autores principales: Li, Chun-Yu, Tu, Can, Gao, Dan, Wang, Rui-Lin, Zhang, Hai-Zhu, Niu, Ming, Li, Rui-Yu, Zhang, Cong-En, Li, Rui-Sheng, Xiao, Xiao-He, Yang, Mei-Hua, Wang, Jia-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156827/
https://www.ncbi.nlm.nih.gov/pubmed/28018221
http://dx.doi.org/10.3389/fphar.2016.00483