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Dysregulation of Ubiquitin-Proteasome System in Neurodegenerative Diseases
The ubiquitin-proteasome system (UPS) is one of the major protein degradation pathways, where abnormal UPS function has been observed in cancer and neurological diseases. Many neurodegenerative diseases share a common pathological feature, namely intracellular ubiquitin-positive inclusions formed by...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156861/ https://www.ncbi.nlm.nih.gov/pubmed/28018215 http://dx.doi.org/10.3389/fnagi.2016.00303 |