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Structural implications of Ca(2+)-dependent actin-bundling function of human EFhd2/Swiprosin-1
EFhd2/Swiprosin-1 is a cytoskeletal Ca(2+)-binding protein implicated in Ca(2+)-dependent cell spreading and migration in epithelial cells. EFhd2 domain architecture includes an N-terminal disordered region, a PxxP motif, two EF-hands, a ligand mimic helix and a C-terminal coiled-coil domain. We rep...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156911/ https://www.ncbi.nlm.nih.gov/pubmed/27974828 http://dx.doi.org/10.1038/srep39095 |