The double-domain cytidine deaminase APOBEC3G is a cellular site-specific RNA editing enzyme

APOBEC3G is a cytidine deaminase with two homologous domains and restricts retroelements and HIV-1. APOBEC3G deaminates single-stranded DNAs via its C-terminal domain, whereas the N-terminal domain is considered non-catalytic. Although APOBEC3G is known to bind RNAs, APOBEC3G-mediated RNA editing ha...

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Detalles Bibliográficos
Autores principales: Sharma, Shraddha, Patnaik, Santosh K., Taggart, Robert T., Baysal, Bora E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156925/
https://www.ncbi.nlm.nih.gov/pubmed/27974822
http://dx.doi.org/10.1038/srep39100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156925/
https://www.ncbi.nlm.nih.gov/pubmed/27974822
http://dx.doi.org/10.1038/srep39100

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