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Rats overexpressing the dopamine transporter display behavioral and neurobiological abnormalities with relevance to repetitive disorders

The dopamine transporter (DAT) plays a pivotal role in maintaining optimal dopamine signaling. DAT-overactivity has been linked to various neuropsychiatric disorders yet so far the direct pathological consequences of it has not been fully assessed. We here generated a transgenic rat model that via p...

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Detalles Bibliográficos
Autores principales: Hadar, Ravit, Edemann-Callesen, Henriette, Reinel, Claudia, Wieske, Franziska, Voget, Mareike, Popova, Elena, Sohr, Reinhard, Avchalumov, Yosef, Priller, Josef, van Riesen, Christoph, Puls, Imke, Bader, Michael, Winter, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156927/
https://www.ncbi.nlm.nih.gov/pubmed/27974817
http://dx.doi.org/10.1038/srep39145