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A Critical, Nonlinear Threshold Dictates Bacterial Invasion and Initial Kinetics During Influenza

Secondary bacterial infections increase morbidity and mortality of influenza A virus (IAV) infections. Bacteria are able to invade due to virus-induced depletion of alveolar macrophages (AMs), but this is not the only contributing factor. By analyzing a kinetic model, we uncovered a nonlinear initia...

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Detalles Bibliográficos
Autores principales: Smith, Amber M., Smith, Amanda P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156930/
https://www.ncbi.nlm.nih.gov/pubmed/27974820
http://dx.doi.org/10.1038/srep38703