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A Critical, Nonlinear Threshold Dictates Bacterial Invasion and Initial Kinetics During Influenza
Secondary bacterial infections increase morbidity and mortality of influenza A virus (IAV) infections. Bacteria are able to invade due to virus-induced depletion of alveolar macrophages (AMs), but this is not the only contributing factor. By analyzing a kinetic model, we uncovered a nonlinear initia...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156930/ https://www.ncbi.nlm.nih.gov/pubmed/27974820 http://dx.doi.org/10.1038/srep38703 |