Phospholipase D1 deficiency in mice causes nonalcoholic fatty liver disease via an autophagy defect

Nonalcoholic fatty liver disease (NAFLD) is characterized by the accumulation of triglycerides (TG) as lipid droplets in the liver. Although lipid-metabolizing enzymes are considered important in NAFLD, the involvement of phospholipase D1 (PLD1) has not yet been studied. Here, we show that the genet...

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Detalles Bibliográficos
Autores principales: Hur, Jang Ho, Park, Shi-Young, Dall’Armi, Claudia, Lee, Jae Sung, Di Paolo, Gilbert, Lee, Hui-Young, Yoon, Mee-Sup, Min, Do Sik, Choi, Cheol Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156943/
https://www.ncbi.nlm.nih.gov/pubmed/27976696
http://dx.doi.org/10.1038/srep39170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156943/
https://www.ncbi.nlm.nih.gov/pubmed/27976696
http://dx.doi.org/10.1038/srep39170

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