Silymarin Protects Mouse Liver and Kidney from Thioacetamide Induced Toxicity by Scavenging Reactive Oxygen Species and Activating PI3K-Akt Pathway

Silymarin (SMN) has been shown to possess a wide range of biological and pharmacological effects. Besides, SMN has antioxidant and free radical scavenging activities. Thioacetamide (TAA) is a well-documented liver toxin that requires oxidative bioactivation to elicit its hepatotoxic effect which ult...

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Detalles Bibliográficos
Autores principales: Ghosh, Shatadal, Sarkar, Abhijit, Bhattacharyya, Sudip, Sil, Parames C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156955/
https://www.ncbi.nlm.nih.gov/pubmed/28018219
http://dx.doi.org/10.3389/fphar.2016.00481

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156955/
https://www.ncbi.nlm.nih.gov/pubmed/28018219
http://dx.doi.org/10.3389/fphar.2016.00481

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