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The Allostery Landscape: Quantifying Thermodynamic Couplings in Biomolecular Systems
[Image: see text] Allostery plays a fundamental role in most biological processes. However, little theory is available to describe it outside of two-state models. Here we use a statistical mechanical approach to show that the allosteric coupling between two collective variables is not a single numbe...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical Society
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156960/ https://www.ncbi.nlm.nih.gov/pubmed/27766843 http://dx.doi.org/10.1021/acs.jctc.6b00841 |