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The Unravelling of the Genetic Architecture of Plasminogen Deficiency and its Relation to Thrombotic Disease

Although plasminogen is a key protein in fibrinolysis and several mutations in the plasminogen gene (PLG) have been identified that result in plasminogen deficiency, there are conflicting reports to associate it with the risk of thrombosis. Our aim was to unravel the genetic architecture of PLG in f...

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Detalles Bibliográficos
Autores principales: Martin-Fernandez, Laura, Marco, Pascual, Corrales, Irene, Pérez, Raquel, Ramírez, Lorena, López, Sonia, Vidal, Francisco, Soria, José Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157013/
https://www.ncbi.nlm.nih.gov/pubmed/27976734
http://dx.doi.org/10.1038/srep39255