Cargando…

Microcystin-Leucine Arginine Causes Cytotoxic Effects in Sertoli Cells Resulting in Reproductive Dysfunction in Male Mice

Microcystin-leucine arginine (MC-LR) is a potent toxin for Sertoli cells. However, the specific molecular mechanisms of MC-induced cytotoxicity still remain unclear. In this study, we performed a comprehensive analyses of changes of miRNAs and mRNAs in Sertoli cells treated with MC-LR. Through compu...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Yabing, Zhou, Yuan, Wang, Jing, Wang, Lihui, Xiang, Zou, Li, Dongmei, Han, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157014/
https://www.ncbi.nlm.nih.gov/pubmed/27976743
http://dx.doi.org/10.1038/srep39238