Genetically manipulated phages with improved pH resistance for oral administration in veterinary medicine

Orally administered phages to control zoonotic pathogens face important challenges, mainly related to the hostile conditions found in the gastrointestinal tract (GIT). These include temperature, salinity and primarily pH, which is exceptionally low in certain compartments. Phage survival under these...

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Detalles Bibliográficos
Autores principales: Nobrega, Franklin L., Costa, Ana Rita, Santos, José F., Siliakus, Melvin F., van Lent, Jan W. M., Kengen, Servé W. M., Azeredo, Joana, Kluskens, Leon D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157022/
https://www.ncbi.nlm.nih.gov/pubmed/27976713
http://dx.doi.org/10.1038/srep39235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157022/
https://www.ncbi.nlm.nih.gov/pubmed/27976713
http://dx.doi.org/10.1038/srep39235

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