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Altered systemic bile acid homeostasis contributes to liver disease in pediatric patients with intestinal failure

Intestinal failure (IF)-associated liver disease (IFALD), as a major complication, contributes to significant morbidity in pediatric IF patients. However, the pathogenesis of IFALD is still uncertain. We here investigate the roles of bile acid (BA) dysmetabolism in the unclear pathogenesis of IFALD....

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Detalles Bibliográficos
Autores principales: Xiao, Yong-Tao, Cao, Yi, Zhou, Ke-Jun, Lu, Li-Na, Cai, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157035/
https://www.ncbi.nlm.nih.gov/pubmed/27976737
http://dx.doi.org/10.1038/srep39264