Plasma cell differentiation is coupled to division-dependent DNA hypomethylation and gene regulation

The epigenetic processes that regulate antibody secreting plasma cells are not well understood. Here, analysis of plasma cell differentiation revealed DNA hypomethylation of 10% of CpG loci that were overrepresented at enhancers. Inhibition of DNA methylation enhanced plasma cell commitment in a cel...

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Detalles Bibliográficos
Autores principales: Barwick, Benjamin G., Scharer, Christopher D., Bally, Alexander P.R., Boss, Jeremy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157049/
https://www.ncbi.nlm.nih.gov/pubmed/27500631
http://dx.doi.org/10.1038/ni.3519

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157049/
https://www.ncbi.nlm.nih.gov/pubmed/27500631
http://dx.doi.org/10.1038/ni.3519

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