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Evaluation of efficacy and safety for recombinant human adenovirus-p53 in the control of the malignant pleural effusions via thoracic perfusion

A certain number of studies have showed that p53 gene transfer has an anti-tumor activity in vitro and in vivo. This study was to evaluate the efficacy and safety of thoracic perfusion of recombinant human adenovirus p53 (rAd-p53, Gendicine) for controlling malignant pleural effusion (MPE). We searc...

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Detalles Bibliográficos
Autores principales: Biaoxue, Rong, Hui, Pan, Wenlong, Gao, Shuanying, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157052/
https://www.ncbi.nlm.nih.gov/pubmed/27976709
http://dx.doi.org/10.1038/srep39355