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Development and validation of a novel bioassay to determine glucocorticoid sensitivity

BACKGROUND: Glucocorticoids (GCs) remain the first line treatment for almost all non-infectious inflammatory diseases, ranging from acute asthma to rheumatoid arthritis. However, across all conditions, patients have a variable response to GCs with approximately 30% being non-responders. This group o...

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Detalles Bibliográficos
Autores principales: Williams, Emily L., Stimpson, Madeleine L., Collins, Peter L., Enki, Doyo G., Sinha, Ashish, Lee, Richard W., Dhanda, Ashwin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157083/
https://www.ncbi.nlm.nih.gov/pubmed/27999674
http://dx.doi.org/10.1186/s40364-016-0079-y