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Clinical implications of repeated drug monitoring of imatinib in patients with metastatic gastrointestinal stromal tumour
BACKGROUND: Imatinib mesylate (IM) is the preferred treatment for the majority of patients with metastatic gastrointestinal stromal tumour (GIST). Low trough IM concentration (C(min)) values have been associated with poor clinical outcomes in GIST patients. However, there are few studies of repeated...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157085/ https://www.ncbi.nlm.nih.gov/pubmed/27999655 http://dx.doi.org/10.1186/s13569-016-0062-2 |